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Progress in development of disease-modifying treatments in Parkinson’s Disease

Henri Huttunen, Chief Scientific Officer, Herantis Pharma Plc, charts progress in the development of disease-modifying treatments for Parkinson’s disease.
image of a gorilla hand showing the function of fingerprints

The function of fingerprints: How can we grip?

Professor Gun-Sik Park, in the Department of Physics and Astronomy at Seoul National University explores the function of fingerprints from a lens of understanding the mechanism of our human ability to grip.
DNA sequencing gel run science and data genomic genetic analysis background abstract pattern.

The link between gene expression and machine learning

Professor Y-h. Taguchi uses tensor decomposition to identify genes associated with altered gene expression caused by drug treatment.
DNA helix colorful genes chromosomes DNA sequence, DNA structure with glow. Science concept background 3d rendering

Genetic coding: Roots of genetic readout in nucleic acid structural duality

Charles W. Carter, Jr, from the Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill explores the roots of genetic readout in the inherent structural duality of DNA and how genetic coding expanded its potential, enabling life to emerge.

PopART: Universal testing and treatment to stop HIV spread

Here, Professor of Epidemiology & International Health Richard Hayes explores and details the PopART study and other trials of Universal Testing and Treatment, a promising strategy to reduce HIV spread.
Kernel Tensor Decomposition

Kernel Tensor Decomposition can improve the drug discovery process

Kernel tensor decomposition and its use in drug discovery for SARS-CoV-2 was vital, however, due to its general method, it has the potential to be used for a wide range of future problems.
heart failure symptom medical heart model showing cardiovascular risk of stroke blood clot with cardiometabolic disease

The haplogroup gap: The ticking time bomb of cardiometabolic disease in developing nations

Cardiometabolic disease (CMD) refers to a cluster of inter-related factors, including obesity, high blood pressure, high blood sugar, and elevated cholesterol (1).

Global food security – Part 4; Enhancing a struggling food system

Professor Curtis R Youngs, the M.E. Ensminger Endowed Chair of International Animal Agriculture at Iowa State University, analyses the flaws of the food system in his fourth part analysis of global food security.
blood transfusion

Genetics and machine learning can improve blood transfusion outcomes

Better blood transfusion outcomes for patients and better protection of the NHS blood supply can be achieved with machine learning, argue Drs Samuel McDermott, Nicholas Gleadall and Sara Trompeter.
Bacteria and viruses illustration

Shrouded in genomic heterochromatin are ancient viral-like elements that could jump

Host defences operate to prevent ‘ancient viruses’ from ever jumping but, in cancers, cells lose multiple layers of ‘epigenetic’ control, and this can lead to the awakening of jumping or ‘retrotransposition’ of ancient viruses.
Hydra in the sea

Understanding Hydra Regeneration

Here, Charisios Tsiairis from Friedrich Miescher Institute for Biomedical Research explores Hydra Regeneration and the genetic programs that make it possible.
tumor cells

Killing cancer softly: The resolution of cancer lies in tumor cells

Dr Dipak Panigrahy, M.D., an Assistant Professor at Harvard Medical School looks at killing tumor cells to resolve the cancer epidemic.
cervical cancer cells, genomic instability

Genomic instability and nuclear architecture in cancer

Sabine Mai and Aline Rangel-Pozzo, at the CancerCare Manitoba Research Institute and The University of Manitoba, Winnipeg, Canada, discuss genomic instability in relation to 3D spatial organisation of telomeres.
Abstract glowing blurry blue DNA texture. 3D Rendering

Mendel, Darwin, and Lysenko: the battle toward understanding genetics

August 1948 saw the Soviet government ban all teaching and research in genetics. Within a year, “the doctrine of agronomist Trofim Lysenko – dubbed ‘Soviet Creative Darwinism’ – replaced genetics in curricula and research plans of biological, medical, veterinary, and agricultural institutions.” (Krementsov 2010).

Stem cell-based therapy for corals

Could medical approaches of stem cell-based therapy, be a tool for corals’ resilience to heat stress? Benyamin Rosental, Principal Investigator, Assistant Professor at Ben Gurion University of the Negev in Israel answers the compelling question here.
autoimmune diabetes

Preventing autoimmune diabetes in genetically susceptible people

Department of Biochemistry - Microbiology and Immunology - University of SaskatchewanCan we now envisage antigen-specific therapies to prevent and treat organ-specific autoimmune diseases, such as autoimmune diabetes?
Virus cells or bacterias under microscope lens

Slight changes can improve much for algorithms looking at gene expressions

Y-h. Taguchi, a Professor at Chuo University, looks at the slight changes made to algorithms when looking at the COVID-19 virus and gene expressions.
type 1 diabetes, insulin

Identifying adult-onset type 1 diabetes

Liping Yu, at the Barbara Davis Center for Diabetes, highlights how we can recognise and diagnose adult-onset type 1 diabetes.
chromosome cells

Satellite DNA arrays barcode chromosomes to regulate genes

In this piece, Dr Helen Rowe summarizes how arrays or strings of multi-copy satellite DNAs can barcode chromosomes to regulate cell fate, by acting...
Long structure of the DNA double helix in depth of view.

What are the possibilities of DNA and RNA sequences?

Serge L. Beaucage, Supervisory Research Chemist at the Food and Drug Administration discusses his work with DNA and RNA sequences and the groundbreaking impact this technique could have.

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