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The Balgrist – medical experts in musculoskeletal injuries

Providing excellent medical service with you in mind

Balgrist University Hospital is recognised worldwide as a highly specialised, leading centre of excellence for assessing, treating and following up on all types of musculoskeletal injuries. The clinic owes its first-rate international reputation to its unique combination of specialised medical services. The hospitals carefully balanced, interdisciplinary network brings together medical specialisms ranging from orthopaedics, paraplegiology, radiology and anaesthesiology to rheumatology and physical medicine under one roof.

The clinics expertise in nursing and its wide range of therapies are complemented by social and psychological support services, legal services, professional integration measures, trial accommodation opportunities and a number of other services.

Research and education

Our teaching activities cover the biological basics of muscle plasticity, and its functional importance in maintaining the musculoskeletal system in both health and disease.

This programme includes university lectures and the research-based education and supervision of Master’s and Doctoral students, as well as junior doctors, in biomedical projects of muscle plasticity in orthopaedics.

Muscle plasticity laboratory

Our research group is concerned with the mechanisms of clinical plasticity in skeletal muscle.

With animal studies and case-orientated clinical studies we are looking for new approaches to unresolved questions on how muscle function is maintained and re-established in the light of orthopaedic surgery.

Current projects include:

  • Molecular and cellular characterisation of the timescale of changes in the muscles after tendon rupture and repair
  • Studies on the effects of genomic factors on muscle plasticity in the context of rehabilitative interventions
  • Pharmacological intervention to suppress skeletal muscle atrophy and the associated increase in intramuscular fat after tendon tears.

To answer these biological questions, we are using state-of-the-art molecular biology techniques, as well as conventional microanatomy and biochemical methods, on biopsy material taken during operations. In particular, we are focussing on the role of adhesive processes in the muscle fibres in regulating mechanical properties of the stress-modulated phenotype of skeletal muscle.

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musculoskeletal function research

A focus on musculoskeletal function research

Here, we feature two extensive interviews with Professor Dr Martin Flück at the Laboratory for Muscle Plasticity at Balgrist University Hospital, about vital musculoskeletal function research.

What are the options for personalised muscle rehabilitation?

Martin Fluck from Balgrist University Hospital outlines options for personalised muscle rehabilitation and research on molecular and cellular mechanisms
A Quest Into Muscle Plasticity

A Quest Into Muscle Plasticity

Muscle weakness and associated poor fatigue resistance is a major challenge to modern Western Society. It arises due to a reduction in the force...