Home Stakeholders Health Research Stakeholders The Genomic Centre for Cancer Research and Diagnosis (GCCRD)

The Genomic Centre for Cancer Research and Diagnosis (GCCRD)

Cutting edge research from The Genomic Centre for Cancer Research and Diagnosis (GCCRD) at the University of Manitoba and CancerCare Manitoba

Molecular imaging at the single cell, sub-cellular and single molecule level in normal and diseased cells is key to scientific and medical advances globally.

Fluorescent imaging reveals structures at the unprecedented resolution of a few nanometres, without the loss of the spatial, three-dimensional (3D) cellular or tissue structure and context. Such information is pivotal to our understanding of disease processes including cancer.

Dr. Sabine Mai established The Genomic Centre for Cancer Research and Diagnosis (GCCRD) as a cutting-edge regional/national imaging facility with a $33M investment with funding from 4 Canada Foundation for Innovation (CFI) grants, funding support from industrial partners, The Province of Manitoba, CancerCare Manitoba, and the University of Manitoba. Recent funding was added by The Canadian Institutes of Health Research (CIHR) through Dr. Mai’s Canada Research Chair (CRC) funding (CRC Tier 1 funding of $1.4 M).

The GCCRD has gained national and international recognition through it workshops and  collaborations with leading national and international researchers in the field. Also, the training of highly qualified personnel in multidisciplinary imaging, and the establishment of novel imaging capabilities within Canada and North America have added to this recognition.

The GCCRD is a member of the Canadian National Scientific Platforms (CNSP), of Bioimaging Canada and Bioimaging North America. It is always open to multidisciplinary collaborations and training.

The GCCRD is located in a 1726 sq ft lab on the 6th floor of the CancerCare Manitoba Research Institute, with adjoining super resolution and image/data analysis rooms, occupying 975 sq ft and 225 sq ft, respectively.

Mission of the GCCRD

  • To foster quantitative imaging of tissues and single cells, including sub-cellular components, and single molecule(s) in normal and diseased cells, for discovery, innovation, knowledge translation, and bench-to-bedside clinical translation.
  • To train the next generation scientists, clinician scientists and clinicians
  • To network between national and international imaging centres and networks.
  • To support all researchers, clinicians, clinician scientists, graduate students and visiting researchers and allow for university-industry collaborations.
  • To offer knowledge translation for patients and their families and for the public.
  • To offer career orientation and short-term projects for high school students.

Vision of the GCCRD

  • To use the power of imaging and its quantitative analysis for discovery and innovation as Canada’s most diversified and advanced imaging facility.
  • To be a reference centre for molecular imaging and training globally.
  • To enhance research and training into single cell, sub-cellular pathways/components and single molecules related to normal and diseased cell functions.
  • To stimulate and support bench to clinic translation.
  • To create image-libraries of normal and tumour cells and tissues in a multi-mode manner (from bright-field to multi-mode fluorescence, from 3D and to super resolution).

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The nuclear architecture of cancer cells

The nuclear architecture of cancer cells

The nuclear architecture of the genome describes the structural order of the genetic information in our cells. It is like a house that protects the family in it, and each room in this house has a role to play, like the kitchen or the living room.