Home 2025

Archives

Photo taken in London, United Kingdom

Semi-synthetic cannabinoids: A potent concern

Semi-synthetic cannabinoids have recently emerged as ‘lighter’ or ‘legal’ alternatives to cannabis, but they may be equally potent and equally risky, younger cousins.

Early intervention in the treatment of people with eating disorders

Tracey Wade from Flinders University highlights the benefits of early interventions for eating disorders. She notes that brief interventions during waiting periods can boost treatment completion rates, and early symptom improvements can lead to better outcomes.
Marrakech cityscape,Morocco.

Male victims of intimate partner violence: Insights from twenty years of research

Denise A. Hines, Ph.D., Enochs Endowed Professor of Social Work at the College of Public Health, George Mason University, explores the often-overlooked issue of male victims of intimate partner violence (IPV).
Abstract defocused light leak background

A call to health policymakers for new directions in suicide prevention and research

Konrad Michel, Professor Emeritus and suicide researcher, argues for a shift away from the traditional medical model of suicide prevention and emphasizes the need to reach the many who don’t see their suicidal thoughts as a mental health issue.
Figure 1. Peripapillary intrachoroidal cavitation (PICC) with a full-thickness defect within the myopic conus. (A). Fundus image showing a circumscribed yellow-orange lesion (black star) at the outer and inferior border of the myopic conus, corresponding to a peripapillary intrachoroidal cavitation. A full-thickness defect (red star) is located within the myopic conus. (B) Section along the green arrow of the infrared image, through the full-thickness defect (red star). The remnant of nerve fibers (yellow arrow) herniate into the PICC cavity. ONH = optic nerve head. Note: Reprinted from Peripapillary Intrachoroidal Cavitation. Adèle Ehongo et al. ‘J. Clin. Med. 2023, 12, 4712’ Originally published by and used with permission from MDPI.

Peripapillary Intrachoroidal Cavitation, a masquerade of normal-tension glaucoma

Dr Adèle Ehongo discusses peripapillary intrachoroidal cavitation (PICC), a masquerade of normal-tension glaucoma.
Mother and child in doctor's office stock photo

Examining childhood multimorbidity: How crucial is studying early life multimorbidity?

Understanding multimorbidity in childhood, where physical and mental health conditions coexist, is crucial. This interview with Dr. Mark Ferro, Canada Research Chair in Youth Mental Health at the University of Waterloo explores its unique challenges compared to adult research, the need for integrated care, key predictors, and vital research directions.
Neuron cells system - 3d rendered image of Neuron cell network on black background. Hologram view interconnected neurons cells with electrical pulses. Conceptual medical image. Glowing synapse. Healthcare concept.

Understanding the role of immune dysregulation in MS

Despite significant progress in MS-related research, challenges remain. Dr Belinda Kaskow and Professor Allan G Kermode from the Perron Institute and The University of Western Australia explore the benefits of investigating the early stages of immune dysregulation in MS to enhance prevention strategies.
Doctor with human thyroid anatomy model. Thyroid tumor and cancer, postpartum period, papillary carcinoma and health

Rethinking papillary thyroid cancer: Why “low risk” isn’t always low impact

Oliver Bathe, Professor of Surgery and Oncology at the University of Calgary and CEO of Qualisure Diagnostics, urges us to rethink papillary thyroid cancer, noting that “low risk” isn’t always synonymous with low impact.
X-ray image of shoulder

Regenerative medicine and osteoarthritis: SVF, exosomes and beyond

Torbjörn Ogéus from Stockholms Led- & Smärtspecialist guides us through the evolving science of stromal vascular fraction, exosomes, and beyond in regenerative medicine and osteoarthritis.
3D rendering illustration soft white organic glossy human brain side view isolated on pastel blue background with separation clipping path for each section

Targeting the brain for the treatment of type 1 diabetes

Michael W. Schwartz, MD, explains the role played by the brain as a cause of elevated blood sugar and related metabolic derangements in type 1 diabetes, and how therapeutic targeting of this brain system can eliminate the need for insulin therapy in animal models.
image: ©Fen EP

Sudden death is the most catastrophic manifestation of heart disease

Any disease affecting the heart muscle (“myocardium”) is a potential cause of sudden cardiac death. Such diseases include recovery following a heart attack (myocardial infarct “MI”) and diseases, such as Hypertrophic and Dilated Cardiomyopathies (HCM, DCM) together with a host of rarer diseases.
Table 1. Twenty conscious EHS symptoms were listed by 1800 and again in 2023-24 from 5G

Defining Electromagnetic Hypersensitivity (EHS)

Michael Bevington, Chair of Trustees at Electrosensitivity UK, examines the history of Electromagnetic Hypersensitivity (EHS) over the past 275 years, highlighting key 18th-century discoveries and early reports of health issues related to electromagnetic fields (EMFs).
Side view mature Caucasian man sitting on living room sofa holding his painful shoulder

Chronic pain and healthcare education in Canada: Bridging the divide

Hansel Lui from the Michael G. DeGroote Institute for Pain Research and Care discusses inadequacies in healthcare education regarding chronic pain management in Canada and opportunities to close these gaps.
Figure 1. Proposed method for creating a holobiont from engineered minimal genome endosymbionts (derived from JCVI-Syn3B) that regenerate progenitor cells in liver tissue. Fluorescently labeled endosymbiont chassis bacteria with a cationic lipid coating (1) pick up protein coronas comprised of blood peptides as they traffic to the liver (2). The labeled bacteria can be visualized in the tissue (3). Once inside the host cells, the engineered endosymbionts secrete transcription factors that affect the genetic circuits of the cell (4), with limited replication with the host cytoplasm (5). After sustained reprogramming by the secreted transcription factors, the function of the holobiont is redirected (6) toward progenitor cells that can regenerate damaged liver tissue (7). Figure created using Biorender.

Tracing evolution’s blueprint: Minimal genome life and the engineering of synthetic endosymbiosis

Roksana Riddle and Christopher H. Contag from Michigan State University discuss the concept of endosymbiosis, how it has evolved, and present strategies to engineering endosymbionts and their applications in developing innovative therapies.
Unrecognizable pharma research scientist selecting the only set of drugs personalized by genome sequencing in a lineup of pills and tablets. Healthcare concept for pharmacogenomics, pharmacogenetics.

CYP genes and haplotypes in personalised medicine

Brian Tait, Chief Scientific Officer at Haplomic Technologies Pty Ltd, focuses here on CYP genes, haplotypes, and their applications in personalised medicine.
Man wearing protective face mask with uv light

Revolutionising indoor air quality to stop pandemics with Germicidal Ultraviolet (GUV) technology

Indoor air quality is a silent public health crisis, harbouring pathogens that contribute to billions of illnesses annually. Addressing this requires urgent attention, and Germicidal Ultraviolet (GUV) technology offers a powerful solution to combat airborne threats.
Two diverse young businesswoman talking and smiling while working on a laptop at a table in an office lounge area

Can premenstrual symptoms help improve women’s healthcare?

Professor Belinda Pletzer from Paris Lodron University of Salzburg explores if the assessment of premenstrual symptoms can help improve women’s healthcare.
Organic curves and glowing particles on a sphere.

Healthy aging: How science and daily habits preserve brain function

Key nutrients like omega-3 fatty acids, curcumin, and NAD+ are important for maintaining cognitive function, but their effective delivery to the brain is hindered by the blood-brain barrier (BBB) and age-related declines in nutrient transport. Dr Rebecca Crews and Heather Makar explore the importance of overcoming these delivery challenges to enhance strategies for cognitive longevity and healthy aging.
Figure 1: Flipons to Learn By: Each Shape Encodes Information Differently and has a different probability of flipping from one conformation to another.

Training your genome

Founder and President of InsideOutBio, Alan Herbert, explores the evolving understanding of genome information storage, and the significance of repetitive sequences called flipons in genome training. These flipons can alter their shape without breaking DNA and are vital in cell biology, especially in responding to environmental stress.
Figure 1: Therapeutic relevance of GPCRs in various diseases.

AI-driven innovations in GPCR ligand synthesis for treating inflammatory diseases

This article explores the significance of G Protein-Coupled Receptors (GPCRs) in therapeutic drug development and strategies for advancing GPCR-targeted therapies, including the use of agonists, antagonists, biased agonism, and allosteric modulators.

Follow Us

Advertisements