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Figure 1. Left ventricular stroke volume relationship to morbidity and mortality in patients ≥12-years-old

Age-related changes in cardiomyopathic phenotype in patients with barth syndrome

With current treatment options for BTHS cardiomyopathic phenotype focused predominantly on alleviating symptoms, Dr Hani N. Sabbah, Director of Cardiovascular Research at Henry Ford Health, explores the potential of more targeted treatment approaches.

Decoding the brain’s role in preventing and recovering from knee injuries

Dustin Grooms, Professor of Clinical Neuroscience at Ohio University, tells us about his research on the brain’s role in shaping injury-risk movement patterns and how this knowledge could aid rehabilitation practices and the development of new therapies to mitigate the risk of knee injuries.
Figure 1: Immunomodulatory therapies are effective during the relapsing-remitting phase of MS, when immune cells are found in active lesions, but fail to ameliorate progressive decline and irreversible clinical disability. Increased axonal injury correlates with lack of immune cell infiltration but sustained activation of resident CNS glial cells in the progressive phase. These pathological findings are consistent with MRI imaging studies demonstrating virtually no new lesions occurring during progressive MS. Additionally, at the time of MS diagnosis there is evidence of prior lesion activity by MRI imaging supporting that the future development of neuroprotective strategies should be administered in combination with immunomodulatory therapies.

Targeting the central nervous system: The future of therapeutic strategies for MS

Tara M. DeSilva from the Department of Neurosciences, Cleveland Clinic, looks at the future of therapeutic strategies for MS, focusing on targeting the central nervous system.
Microscopic photo of a professionally prepared slide demonstrating Plasma cell myeloma from bone marrow aspirate. Wright Giemsa stain.

Developing novel therapies for childhood cancers

Dr Peter J Houghton from Greehey Children’s Cancer Research Institute discusses the obstacles in developing new treatments for childhood cancers and new approaches in preclinical testing.
A beautiful and strong athletic young woman working hard cross fitness workout in low light gym working with medicine ball.

The mechanisms and benefits of exercise

At Wayne State University, Robert Wessells and his team are making significant strides in identifying potential exercise mediators or mimetics that could help mitigate pathologies resulting from prolonged sedentary periods.
Scientific analysis of Alzheimer's disease in hospital, conceptual image

Lecanemab and other treatments: Glimmers of hope for alzheimer’s patients

Effective treatments for amyloid-associated neurological diseases are desperately needed; H. Robert Guy, CEO of Amyloid Research Consultants, talks us through the obstacles and opportunities associated with structure-based drug design.
Human brain hologram on black background

Pain regulation and research: Decoding the brain’s response to pain

Professor Patrick Stroman from the Centre for Neuroscience Studies at Queen’s University shares insights into his research on the neural basis of human pain and pain regulation, which is supported by functional magnetic resonance imaging.

The evolution of continuous glucose monitoring and advancing monitors

Afon Technology Ltd explains how its continuous glucose monitoring (CGM) device provides a non-invasive and pain-free solution for people with diabetes.
Abstract Rainbow Blockchain Pixel Shape Prism Exploding Glitch Futuristic Pattern Funky Offbeat Aspirations Neon Surreal Bandwidth Glowing Flowing Time Machine Nanoparticle Firework Confetti Lens Flare Vitality Zoom Effect Cryptocurrency Mining Stereoscopic Distorted Digitally Generated Image Fractal Fine Art for banner, flyer, card, poster, brochure, presentation 16x9 Format

What is at stake in the psychedelic renaissance?

Professor Erika Dyck, Canada Research Chair in the History of Health & Social Justice, discusses the extensive history and growing medical application of psychedelics known as the psychedelic renaissance.
microbiology, rare diseases

Overcoming obstacles in rare disease clinical trials

With an urgent need to develop new treatments for people with rare diseases, the University of Birmingham’s Professor Timothy Barrett explains how a new consortium will provide a step change in the delivery of rare disease clinical trials.
African American mature man practicing with power band on exercise class in nature.

Healthy aging and physical activity practice: The missing link

Isabelle J. Dionne, PhD, Professor, Université de Sherbrooke, walks us through physical activity practice and how it impacts research on healthy aging.
AMR,

Bacteriophages: Nature’s remedy for tackling superbugs and antimicrobial resistance

Given the increasing threat of antimicrobial resistance, Gunther Vanwezer, CEO of Vésale Bioscience, explains how bacteriophages offer a promising natural solution and outlines the company’s efforts to become a pioneer in the development of innovative, personalised and sustainable phage-based therapy solutions.
Cancer outbreak and treatment for malignant cancer cells in a human body caused by carcinogens and genetics with a cancerous cell as an immunotherapy symbol and medical therapy as a 3D render.

Ultravision joins the fight against peritoneal cancer

Considering the high, unmet medical need associated with peritoneal metastases, Dr Dominic Griffiths, CEO of Alesi Surgical Ltd, outlines how the company’s innovative Ultravision technology could dramatically improve clinical outcomes for patients with the disease.
holding diabetic measurement tools, apple on table .

Patients with diabetes in rural underserved areas

Richard J. Santen, MD, Emeritus Professor of Medicine at the University of Virginia in Charlottesville, Virginia, USA, delineates the characteristics of patients with diabetes residing in rural underserved areas, including the role of meal replacements for weight loss.
Wireframe of the internal structure of the human ear. 3D. Front view. Vector illustration.

Glutamate excitotoxicity in the cochlea

Mark Rutherford, Associate Professor at Washington University School of Medicine, discusses the burden and causes of hearing dysfunction, as well as the possible solutions for mitigating glutamate excitotoxicity.
Symbolic illustration of infectious viruses under the microscope, for example influenza viruses, smallpox, measles or similar. Medical research and investigation of diseases and healthcare concept.

The role of microbial diversity in microbial electrosynthesis

Bacteria are often painted as the enemy of humanity. Before the discovery of antibiotics, a wound getting infected was frequently a death sentence.
Man medicating himself at home medicine

Using psychedelics to mitigate Treatment Resistant Depression

Cosmo Feilding-Mellen, CEO, Beckley Psytech, charts the role of psychedelics in mitigating Treatment Resistant Depression.
Futuristic laboratory equipment. Brainwave scanning research on computer screens

Exploring neurological & mental brain disorders in Europe

European Brain Council provides a very helpful update on Brain disorders in Europe – neurological and mental alike.
Girl Undergoing Eye Examination

Sight loss research: Looking forward to an equitable future

Keith Valentine, Chief Executive of Fight for Sight and Vision Foundation, shares how these newly merged organisations are driving efforts in sight loss research to improve patient care.

Keep your teeth for life, but how?

Drs Marcel Donnet and Neha Dixit discuss the importance of teeth cleaning and how the innovative AIRFLOW® PLUS powder can tackle biofilm and safeguard oral health.

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