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Identifying potential exercise mediators
Dr Robert Wessells and his team at Wayne State University are researching exercise mediators and mimetics in fruit flies (Drosophila melanogaster) to explore how to provide the benefits of exercise to individuals who are unable to access it. Here, he shares what he has discovered during his research.
Novel imaging platform for early and precise cancer diagnosis
Regina Gumenyuk, Adjunct Professor at Tampere University, is exploring a novel imaging platform for early and precise cancer diagnosis. Read more about this exciting innovation here.
Common data elements to advance ME/CFS research
Standardizing data collection in ME/CFS research through Common Data Elements is a crucial step toward improving diagnosis, advancing treatments, and fostering collaboration across studies to accelerate progress in understanding this complex disease.
Amphibole asbestos as a public health risk in 2025: Autoimmune disease
Despite efforts to minimize exposure, deaths from asbestos-related diseases remain high. A recent review emphasized the importance of evaluating different mineral groups and pointed out that exposure to amphibole asbestos is linked to higher rates of autoimmune diseases. Jean C. Pfau and Brenda J. Buck discuss the urgent need to address this public health risk more effectively.
Mental health research: The healing power of indigenous drumming
Gilles Comeau, Senior Scientist at the University of Ottawa, Institute of Mental Health Research at The Royal, explores the healing power of Indigenous drumming
Drumming...
Consideration of key issues in positioning early intervention for eating disorders
Tracey Wade from the Flinders University Institute for Mental Health and Wellbeing outlines several key issues to consider in developing successful early intervention approaches for people with disordered eating and who are at risk of developing an eating disorder.
Bioinformatics into TB surveillance: A new approach to an ancient foe
David Ussery, a Professor in the Department of BioMedical Informatics at UAMS, and his Ph.D. student Brian Delavan discuss bioinformatics into TB surveillance, presenting a new approach to tackling this ancient foe.
Process intensification: A game changer for the pharma market
Deborah McElhone, Head of Sustainability (Pharma) from CPI, argues that process intensification is a game changer for the pharma market.
Feline coronavirus and feline infectious peritonitis (FIP) – Russian roulette for your pet
Utilising Machine Learning on clinical datasets could help to crack the enigma of feline infectious peritonitis diagnosis.
Personalized medicine in oncology: Small molecule inhibitors, biologics and immunotherapies
Priya Hays, PhD, CEO of Hays Documentation Specialists, discusses innovations and advancements in the development and evaluation of personalized cancer therapies.
Stem cell exhaustion and its role in healthy aging
Scientist Sarallah Rezazadeh from the Icahn School of Medicine explores the molecular mechanisms behind adult stem cells as we age.
Understanding the link between PICC and myopic complications
Dr Adèle Ehongo discusses the pathogenesis of peripapillary intra-choroidal cavitation and its implications for myopic complications.
Prenatal cannabis exposure and its lasting impact on memory
Professors Miranda Reed from Auburn University and Vishnu Suppiramaniam from Kennesaw State University have studied how prenatal cannabis exposure affects brain development and cognitive functions, including memory.
Predicting cancer risk with computational biology
Andrew Teschendorff, Professor at the Chinese Academy of Sciences, is developing computational systems-biological tools to identify cells at risk of turning cancerous.
The neuroscience of metabolism
Given that the brain can detect and respond to changing levels of body fat and blood sugar, Michael W. Schwartz, MD from the University of Washington Medicine Diabetes Institute, explains how the brain can be targeted to treat obesity and diabetes.
The microbiome and aging: Unlocking new frontiers in healthy longevity
Research conducted by the USF Microbiomes Institute and the MiaGB Consortium is uncovering the significant link between microbial communities and host biology. This understanding could lead to new therapies for age-related conditions. Shalini Jain, Christian Brechot, and Hariom Yadav provide further insights.
Rethinking the reproductive clock: Can NAD+ preserve fertility?
Recent research indicates that the compound NAD+ offers a promising solution to support fertility and reproductive longevity.
![Figure 1. Systemic immune responses elicited by oral dmLT-saponin combinations compared to injected vaccines (A) Cryo-electron microscopy (cryo-EM) image of the dmLT and saponin formulation demonstrating the formation of acid-stable micelle particles upon the addition of saponin to dmLT. (B) Preclinical evaluation of systemic serum IgG and IgA antibody responses following prime/boost vaccination. Antibody levels against the microbial protein antigen included in the vaccination were assessed two weeks post-final vaccination in immunized mice. Groups were stratified by vaccination route (intramuscular [IM] or sublingual [SL]) and adjuvant formulation (dmLT [D] and/or saponin [S]). Comparisons with unvaccinated controls (white bars) are shown. Statistical significance between groups is indicated (*P < 0.05), with the SL D+S group achieving the best IgG and IgA responses to vaccine antigen.](https://www.openaccessgovernment.org/wp-content/uploads/2025/01/Figure-01-218x150.jpg "New strategies for an old problem – Oral vaccines research")
New strategies for an old problem – Oral vaccines research
Despite their advantages, oral vaccines encounter several challenges. Professor Elizabeth Norton from Tulane University discusses how her team is addressing these issues and their research on developing and testing dmLT and saponin combination adjuvants.
Teen relevant and open access health information for building vaccine confidence
With the abundance of health information about vaccines online, there is a need for an open educational resource (OER) that empowers youth to understand the importance of vaccines and make informed medical choices.
Computational psychiatry and the opioid crisis: A deep dive
In this interview, we speak with Dr. Bo Cao, a leading expert in computational psychiatry at the University of Alberta, Canada. Dr. Cao discusses how advanced data analysis and machine learning are transforming our approach to the opioid crisis and mental health care, offering new hope in addressing one of North America’s most pressing public health challenges.
