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The microbiome in early life: Setting the stage for optimal early life health in...
Researchers at the University of South Florida Microbiomes Institute are exploring exciting new areas in microbiome research; here, they discuss the essential role that the microbiome plays in early life health.
Manufactured chemicals: A significant contributor to chronic childhood diseases
Pamela J. Lein from the University of California, Davis, discusses manufactured chemicals as a significant contributor to chronic childhood diseases.
Antibiotics in tuberculosis treatment: Impacts on the respiratory microbiome and the role of optimal...
The respiratory microbiome plays a crucial role in maintaining immune regulation. In this article, Dr Wilber Sabiiti emphasizes the need for optimized antibiotic dosing strategies to minimize harmful effects on the microbiome and improve treatment outcomes for patients with TB.
Joint sounds, how do they arise?
A key aspect of joint manipulation is the audible sounds that may occur during manipulation, which are believed to result from a phenomenon known as tribonucleation. Dr Rob Sillevis from.
Carbon-neutral lifestyle changes and their impact on future health in cities
Dr Peter Hoffmann and Deniz Sirin at Climate Service Center Germany explore carbon-neutral lifestyle changes and their impact on future health in cities.
Daily cigarette smoking research from the Global Flourishing Study
Sung Joon Jang from the Institute for Studies of Religion, Baylor University and Pepperdine University, shares some of the new findings about daily cigarette smoking from the Global Flourishing Study.
Early intervention in the treatment of people with eating disorders
Tracey Wade from Flinders University highlights the benefits of early interventions for eating disorders. She notes that brief interventions during waiting periods can boost treatment completion rates, and early symptom improvements can lead to better outcomes.
Peripapillary Intrachoroidal Cavitation, a masquerade of normal-tension glaucoma
Dr Adèle Ehongo discusses peripapillary intrachoroidal cavitation (PICC), a masquerade of normal-tension glaucoma.
Regenerative medicine and osteoarthritis: SVF, exosomes and beyond
Torbjörn Ogéus from Stockholms Led- & Smärtspecialist guides us through the evolving science of stromal vascular fraction, exosomes, and beyond in regenerative medicine and osteoarthritis.
Defining Electromagnetic Hypersensitivity (EHS)
Michael Bevington, Chair of Trustees at Electrosensitivity UK, examines the history of Electromagnetic Hypersensitivity (EHS) over the past 275 years, highlighting key 18th-century discoveries and early reports of health issues related to electromagnetic fields (EMFs).
Advancing materials science: Translating innovative research to commercial prospects
Aarthi Janakiraman, Research Director of the Advanced SciTech Division at Everest Group, focuses on advancing materials science and translating innovative research into commercial opportunities.
Revolutionising indoor air quality to stop pandemics with Germicidal Ultraviolet (GUV) technology
Indoor air quality is a silent public health crisis, harbouring pathogens that contribute to billions of illnesses annually. Addressing this requires urgent attention, and Germicidal Ultraviolet (GUV) technology offers a powerful solution to combat airborne threats.
The challenge of determining the health risks of low-dose chemical exposures
Rebecca J. Wilson and Pamela J. Lein, explore whether the dose makes the poison or not. Here, they discuss the challenges of determining health risks associated with low-dose chemical exposures.
Quantitative reasoning in higher education: The 5C Model
Quantitative reasoning enhances and lengthens lives. Professor Gregory Foley of Ohio University discusses how his team is improving QR instruction in U.S. higher education.
Common data elements to advance ME/CFS research
Standardizing data collection in ME/CFS research through Common Data Elements is a crucial step toward improving diagnosis, advancing treatments, and fostering collaboration across studies to accelerate progress in understanding this complex disease.
![Figure 1. Systemic immune responses elicited by oral dmLT-saponin combinations compared to injected vaccines (A) Cryo-electron microscopy (cryo-EM) image of the dmLT and saponin formulation demonstrating the formation of acid-stable micelle particles upon the addition of saponin to dmLT. (B) Preclinical evaluation of systemic serum IgG and IgA antibody responses following prime/boost vaccination. Antibody levels against the microbial protein antigen included in the vaccination were assessed two weeks post-final vaccination in immunized mice. Groups were stratified by vaccination route (intramuscular [IM] or sublingual [SL]) and adjuvant formulation (dmLT [D] and/or saponin [S]). Comparisons with unvaccinated controls (white bars) are shown. Statistical significance between groups is indicated (*P < 0.05), with the SL D+S group achieving the best IgG and IgA responses to vaccine antigen.](https://www.openaccessgovernment.org/wp-content/uploads/2025/01/Figure-01-218x150.jpg "New strategies for an old problem – Oral vaccines research")
New strategies for an old problem – Oral vaccines research
Despite their advantages, oral vaccines encounter several challenges. Professor Elizabeth Norton from Tulane University discusses how her team is addressing these issues and their research on developing and testing dmLT and saponin combination adjuvants.
A legacy of medicine and biodiversity: Protecting the cinchona tree
The endangered Cinchona officinalis, native to the Andean foothills, produced the world’s first anti-malarial drug. Augusta Cueva-Agila explains why it is crucial to conserve this species and how conservation efforts can be implemented.
The European Cancer Pulse: From data intelligence to policy action
Norbert Couespel 1 and Mark Lawler 1, 2 highlight the European Cancer Pulse, a critical tool in tracking cancer inequalities and influencing cancer policy in Europe.
Predicting cochlear implant performance: Moving beyond single biomarkers and leveraging artificial intelligence
Matthew Shew, Amit Walia, and Craig A. Buchman highlight that the significant variability in speech perception among cochlear implant users can be addressed by using a multi- faceted approach that incorporates emerging technologies like machine learning and artificial intelligence to improve outcome prediction models.
CRISPR/ Diagnostics: A portable lab for everyone
Professor Kevin J. Zwezdaryk and Chandler H. Monk discuss CRISPR and diagnostics, focusing on the development of a portable lab accessible to everyone.
