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Diseases & Conditions

UK’s first citizen‑led lead exposure screening in children launches in Leeds

A pioneering study, the Elevated Childhood Lead Interagency Prevalence Study (ECLIPS), has launched in Leeds to screen children aged 1–6 for lead exposure using home-based finger‑prick blood tests, soil and dust sampling, and surveys.

New gene therapy could prevent kidney damage in people with type 1 diabetes

University of Bristol researchers have discovered a VEGF-C gene therapy that protects the kidneys and may prevent serious complications in people with type 1 diabetes.

Nanomedicine breakthrough: Nanoparticles reverse Alzheimer’s pathology in mice

A UCL-led study shows bioactive nanoparticles can restore blood-brain barrier function and clear amyloid-β in mice, reversing Alzheimer's-like brain changes.

NHS to screen newborns for life-threatening metabolic disorder HT1

A new NHS screening programme will test babies for hereditary tyrosinemia type 1 at five days old, enabling early treatment to prevent organ damage, liver failure, and other serious complications.

COVID-19 could cost UK £7 billion a year without autumn vaccinations

A new OHE model shows that stopping annual autumn COVID-19 vaccinations could cost the UK economy £7 billion each year.

Clean air could prevent thousands of late-life eczema cases, UK Biobank study finds

A UK Biobank study of over 300,000 participants reveals that reducing air pollution could prevent nearly 16% of late-onset eczema cases.

New study reveals how microplastics may affect human health

A new study shows microplastics can alter gut bacteria, mimicking changes linked to depression and colorectal cancer.

First-of-its-kind study investigates vaping’s impact on lung health

The University of Birmingham leads £1.55m research to assess the long-term effects of vaping on respiratory cells, immunity, and lung microbiome in smokers.

AI-powered blood test detects Alzheimer’s early

The University of Liverpool researchers create a low-cost, handheld AI-powered blood test to detect Alzheimer's biomarkers, enabling earlier diagnosis and global accessibility.

Parkinson’s disease trigger observed in human brain tissue for the first time

Scientists have directly visualised alpha-synuclein oligomers in human brain tissue, a key trigger in Parkinson's disease.

Entelli-02 phage therapy targets antibiotic-resistant superbugs in hospitals

Monash University researchers develop Entelli-02, a precision phage therapy cocktail effective against multidrug-resistant Enterobacter cloacae complex.

NIH launches first dedicated organoid center to reduce animal testing

The NIH has established the Standardized Organoid Modeling Center, aiming to develop reproducible, human-based models using AI and robotics, reducing reliance on animal testing.

Gene therapy shows a breakthrough in slowing Huntington’s disease progression

A new gene therapy called AMT-130 has shown promising results in slowing the progression of Huntington’s disease, according to the latest results from a global clinical trial.

Advancing rare diseases care

Lorna Rothery spoke with Victoria Hedley, co-lead of the Rare Disease Research UK Hub, about initiatives aimed at advancing the agenda for rare diseases, as well as the importance of facilitating cross-border collaboration to promote best practices and advance critical research.

Fossil fuels threaten global health at every stage of life, a new report warns

A new report starkly reveals the severe and wide-ranging damage that fossil fuels inflict on human health, from the earliest stages of life to old age.

Scientists reverse stroke damage with stem cell therapy

Scientists have achieved a significant breakthrough in stroke recovery, using stem cell therapy to repair stroke damage in mice.

Making the NHS 10-year Health Plan for England deliver for dementia

Beth Clayton-Exworth of Dementia UK outlines steps for the NHS 10-Year Plan to improve care for the UK’s one million people with dementia.

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