Peter J. Houghton received his Ph.D. from the University of London (Institute of Cancer Research) 1977
He joined the faculty of St. Jude Children’s Research Hospital in Memphis Tennessee and became Chair of Molecular Pharmacology (1992-2009) and co-lead for the Solid Malignancies Program (1988-2009).
Dr. Houghton became Director, Childhood Cancer and Blood Diseases, Nationwide Children’s Hospital (2009-2014), and subsequently Director Greehey Children’s Cancer Research Inst. San Antonio (2014-2020); He is Professor Emeritus, Molecular Medicine, UTHSA, and has published approximately 380 peer-reviewed articles focused on childhood cancer.
He pioneered development of patient derived xenografts (PDXs) as preclinical models and has used these to develop novel therapeutics largely focused on pediatric sarcoma and more recently on BRAF-mutant glioma. Dr. Houghton is currently supported by grants from the National Cancer Institute and the Cancer Prevention and Research Institute of Texas (CPRIT).