Greehey Children’s Cancer Research Institute works to advance scientific knowledge relevant to childhood cancer
Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to understanding it’s causes, and accelerate the translation of knowledge into novel therapies. Greehey CCRI strives to have national and global impact on childhood cancer by discovering, developing, and disseminating new knowledge.
Our mission has three key areas – research, clinical and education. Research strengths include cancer genomics, DNA damage, RNA biology, and drug development. We are developing expertise in drug delivery, focusing on nanotechnology-driven delivery of small RNA mimics and inhibitors.
The Pediatric Translational Working Group, formed as part of the NCI supported Mays Cancer Center, meets regularly to coordinate discoveries to develop novel therapies. Members of the Greehey CCRI faculty have engaged in identifying novel drugs and biologicals as part of the NCI supported Pediatric Preclinical Testing Program/Consortium (PPTP/C) and PIVOT programs. This work has facilitated more rapid development and prioritization of new agents for pediatric clinical trials.
Dr. Houghton is Professor Emeritus at Greehey CCRI and has his academic appointment in Molecular Medicine. Dr. Houghton has been continuously funded by the National Cancer Institute (NCI) for almost 40 years and currently has projects supported to develop novel drugs for pediatric cancer and BRAF-mutant childhood glioma.