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Clinical Trials

10-Year NHS Health Plan delivers major boost to UK clinical trials

The government has unveiled a transformative initiative that will empower millions of NHS patients to find and join clinical trials via the NIHR’s “Be Part of Research” portal within the NHS App.

Psychedelic therapy with psilocybin relieves depression in cancer patients

New results from a clinical trial reveal that a single dose of psilocybin can provide sustained reductions in depression and anxiety in individuals with cancer suffering from major depressive disorder.

Early dog exposure may reduce childhood eczema risk

Having a pet dog may lower the risk of eczema in children who are genetically prone to the condition, shedding light on how environmental factors may influence genetic risks.

Scientists unveil terbium-161 breakthrough in targeted lymphoma treatment

A groundbreaking study from the Paul Scherrer Institute (PSI) in collaboration with Inselspital–Bern University Hospital has unveiled a promising new therapy for lymphoma using the radioactive isotope terbium-161.

Adult-onset type 1 diabetes increases the risk of cardiovascular disease

A new study reveals that adults diagnosed with type 1 diabetes face a heightened risk of cardiovascular disease and death, with no better prognosis than those diagnosed in childhood.

Low-dose interleukin-2 found safe and effective for slowing motor neurone disease progression

A major clinical trial has found that low-dose interleukin-2 (IL2LD) is safe and may significantly extend survival in people with motor neurone disease (ALS).

Transforming radiotherapy research and treatment through continued innovation

Professor David Sebag-Montefiore outlines the profound impact of radiotherapy research. Through global trials and personalised approaches, innovation advances cancer care. Collaborative efforts ensure patient-centred treatments, paving the way for smarter, kinder therapies and a future of precision oncology.

Sotatercept approved for pulmonary arterial hypertension

A new treatment, Sotatercept, for pulmonary arterial hypertension (PAH) has recently been approved by the Medicines and Healthcare Products Regulatory Agency (MHRA).

Gene therapy can restore vision in patients with rare inherited condition

Researchers at the Perelman School of Medicine at the University of Pennsylvania have reported improvements in vision among patients with a rare inherited condition, following gene therapy.

HIV vaccine candidate shows early success in clinical trial

An HIV vaccine candidate developed at the Duke Human Vaccine Institute has demonstrated the ability to trigger low levels of a rare type of neutralising antibodies (bnAbs) in a small group of participants.

Can listening to classical music reduce babies’ pain levels?

A new study suggests that playing Mozart's lullaby may reduce pain levels in newborn babies undergoing heel prick blood tests.

Testing the clinical mechanisms of ADHD with depression and gender

£2.4 million has been funded to trials evaluating the clinical mechanisms of ADHD, with consideration to its progression with depression, parental impact, and ADHD in women.

Advancing animal rights

With a particular focus on South Korea, Open Access Government explores the changing perceptions around animal welfare and some of the policies introduced to support this.

Experimental Alzheimer’s drug slows progression of early disease

An experimental Alzheimer's drug called donanemab, developed by Eli Lilly, has demonstrated a slowdown in progression of disease at early stages, according to trial data.

Understanding primary biliary cholangitis

Chronic liver diseases can have a detrimental impact on physical and mental health; we explore the underlying causes, symptoms, and treatment for primary biliary cholangitis.

Is fusobacterium responsible for the formation of endometriosis?

Fusobacterium, implicated in diseases like gingivitis, ulcerative colitis, and colon cancer, has now been discovered to play a role in the formation of endometriosis.

Phasing out the use of animals in science

Barney Reed, Senior Scientific Manager, Animals in Science Department at the RSPCA, stresses the need for ambitious strategies for phasing out the use of animals in science.

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