A first-in-patient trial using AAV-based OTOF gene therapy, led by Karolinska Institutet and Chinese hospitals, restored hearing (improving from 106 dB to 52 dB) in 10 individuals aged 1–24.
George Ordiway, a PhD student in the laboratory of Dr. Jason Tait Sanchez at Northwestern University, discusses how patterned activity in the nervous system permits a wide range of biologically relevant functions, including auditory development.
PhD students Courtney Coburn Glavin, Kailyn A. McFarlane, and Assistant Professor Jason Tait Sanchez discuss the mechanisms, barriers, and future progress for hearing speech in noisy environments.
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