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concept of DNA

Exploring the science behind gene therapy in treating genetic diseases

Professor Alan Boyd explains the science behind gene therapy, the challenges in treating genetic diseases, and current trends in the sector.
treat osteogenesis imperfecta

Stem cell & gene therapy to treat osteogenesis imperfecta: hype or hope

Pascale V Guillot from University College London, Elizabeth Garrett Anderson Institute for Women’s Health, explains stem cell and gene therapy to treat osteogenesis imperfecta, but is this hype or hope?
gene therapy field

What are the challenges surrounding gene therapy today?

Dr Jen Vanderhoven, Director, National Horizons Centre, Teesside University, sheds some light on how the gene therapy field can progress in the face of funding challenges and skills shortages.
restore eyesight, gene therapy

Scientists successfully use gene therapy to restore eyesight 

Scientists in France have partially restored the eyesight of a blind man, using gene therapy - he is now able to identify blurry shapes.
new gene therapy, OPA1

New gene therapy for eye disease developed in Ireland

Scientists from Trinity College Dublin have developed a new gene therapy for an eye disease that leads to progressive loss of vision.
diabetic retinopathy

Repurposing FDA-approved medicines and gene therapy to combat diabetic retinopathy

Lalit Singh Pukhrambam, PhD, and Ahmed S Ibrahim, PhD from Wayne State University School of Medicine in the U.S. focus here on the importance of combating diabetic retinopathy.
human gene therapy

AAV: From almost a virus to an awesome vector for human gene therapy

Dr. Arun Srivastava, George H. Kitzman Professor of Genetics, from the University of Florida describes the rationale and strategies for the development of next generation (NextGen), generation X (GenX) and optimised (Opt) recombinant AAV vectors for human gene therapy Recombinant AAV vectors have been, or are currently being, used in...
eye health

Eye health: Testing the safety of stem cell therapy for age-related macular degeneration

Kapil Bharti, PhD, Senior Investigator and Head of the Ocular and Stem Cell Translational Research Section at the National Eye Institute (NEI), explains testing the safety of a stem cell therapy for age-related macular degeneration in this special focus on eye health.
Duchenne muscular dystrophy

Duchenne muscular dystrophy: A test case for gene-targeted therapy development in rare disease

Laura Hagerty, PhD, Scientific Portfolio Director at the Muscular Dystrophy Association, highlights strategies for gene correction to treat Duchenne muscular dystrophy.
next generation cancer immunotherapy

Nano DDS technology contributes to next-generation cancer immunotherapy

Dr Takashi Nakamura from Hokkaido University challenges the potential of nano-tech based drug delivery system (Nano DDS) in the development of next-generation cancer immunotherapy.
ID 63640029 © Milkovasa | Dreamstime.com

The regenerating spiny mouse and its potential for human therapy discovery

Discovering cures for human diseases or how to recover from damage or trauma to tissues is the fundamental goal of medical researchers, but it is a daunting task. Nevertheless, recent studies have shown the remarkable potential of the spiny mouse in addressing these crucial issues
spinal muscular atrophy

Spinal muscular atrophy (SMA) – research from gene and modifiers to therapy

The fascinating research of Professor Brunhilde Wirth is placed under the spotlight, concerning her work in the field of disease-causing genes, modifier pathways and pathomechanisms of neuromuscular disorders, focussing on spinal muscular atrophy (SMA)

New concepts for the pathogenesis and asthma therapy

Prof Dr. Michael Roth, University Hospital Basel looks at how asthma therapy can reduce the effects of airway wall remodelling
Photomicrograph of Metastatic adenocarcinoma of lung. Pleural fluid FNAC. 200X

Photodynamic Therapy: Killing cancer gently with visible light

Photodynamic therapy, using visible light with lower energy, causes fewer side effects when treating cancer, find Drs. Mary Potasek, Evgueni Parilov, and Karl Beeson, Co-founders of Simphotek, Inc.
Healthcare And Medical Industry Imagery

Improving cancer therapy using sonoenhancement with acoustic cluster therapy

Sonoenhancement with Acoustic Cluster Therapy (ACT®) improves drug delivery to solid tumors, and by that reduces the necessary doses and side effects.
Stressed woman working in modern office. Frustrated businesswoman with head in hands sitting on desk in the office.

Link between premature menopause, later hormone therapy and Alzheimer’s disease

Researchers are investigating the role of tau in the link between early menopause, delayed hormone therapy and Alzheimer's disease.

Peroxisomes, lipids, and neurodegeneration

Prof. Michael Schrader at the University of Exeter looks to understand the role of peroxisomes in human health and disease.
Shot of a mother and her daughter playing together on a merry-go-round at the park

Paediatric autism communication therapy improved long-term child outcomes

Paediatric Autism Communication Therapy is currently the only scientifically evidenced early social communication intervention to demonstrate long-term improved child social communication outcomes into middle childhood Despite Autism being an enduring condition affecting 2% of people globally, evidenced intervention to improve the developmental impairments is limited. Paediatric Autism Communication Therapy (PACT)...
A senior Canadian man with prostate cancer opens a blister pack to release a dose of nonsteroidal antiandrogen. Bicalutamide. Ambient light inside a dining room in a British Columbia home.

What are the cardiovascular risks of hormone therapy?

Individuals suffering from gender dysphoria may decide to take hormone therapy, but a new study says that this treatment can increase the risk of serious cardiac events.
Lady suffering from strong stomach ache, gastritis, problems with bladder

Incontinence treatment through bioelectrical implant therapy

In a current incontinence treatment, researchers are exploring how to physically regulate bladder function by bioelectrical implant signals.

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