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Clinical Trials

MHRA approves Tofersen for rare inherited form of motor neurone disease

The MHRA has approved Tofersen to treat SOD1-related motor neurone disease (MND), a rare inherited form of the condition.

Testing the clinical mechanisms of ADHD with depression and gender

£2.4 million has been funded to trials evaluating the clinical mechanisms of ADHD, with consideration to its progression with depression, parental impact, and ADHD in women.

Advancing animal rights

With a particular focus on South Korea, Open Access Government explores the changing perceptions around animal welfare and some of the policies introduced to support this.

Experimental Alzheimer’s drug slows progression of early disease

An experimental Alzheimer's drug called donanemab, developed by Eli Lilly, has demonstrated a slowdown in progression of disease at early stages, according to trial data.

Understanding primary biliary cholangitis

Chronic liver diseases can have a detrimental impact on physical and mental health; we explore the underlying causes, symptoms, and treatment for primary biliary cholangitis.

Is fusobacterium responsible for the formation of endometriosis?

Fusobacterium, implicated in diseases like gingivitis, ulcerative colitis, and colon cancer, has now been discovered to play a role in the formation of endometriosis.

Phasing out the use of animals in science

Barney Reed, Senior Scientific Manager, Animals in Science Department at the RSPCA, stresses the need for ambitious strategies for phasing out the use of animals in science.

Phasing out the use of animals in science

Barney Reed, Senior Scientific Manager, Animals in Science Department at the RSPCA, stresses the need for ambitious strategies for phasing out the use of animals in science.

“No child should be going blind from ROP”: AI as a solution to childhood blindness

A revolutionary AI tool can predict retinopathy of prematurity (ROP), paving the way for the prevention of childhood blindness.

The Clinical Pathway DevOps Platform to help NHS staff efficiency

Nathan Moore, Director at Primum Digital Ltd looks toward helping NHS staff deliver the best care at a reduced carbon cost.

Gender gaps in drug trials harm women’s health through overmedication

When conducting drug trials, it is vital to include women and men in research to prevent gender gap issues like adverse drug reactions.

Talking therapy for self-harm trial “could make a huge difference”

The National Institute for Health and Care Research (NIHR) launches a new talking therapy for self-harm trial in an effort to reduce the number of those struggling in the UK.

Research, innovation and health inequalities of blood transfusion

Open Access Government investigates the rudiments of blood transfusion, focussing on research in the field and health inequalities.

Long COVID lessons learned beyond the pandemic

The Long COVID lessons learned beyond the COVID-19 pandemic are detailed here by leading Professors working on the University College London STIMULATE-ICP programme.

Tuberculosis drug regimens and their efficacies

Andrew Nunn, Professor of Epidemiology in the Medical Research Council Clinical Trials Unit at UCL, analyses different tuberculosis drug development regimens.

Secure remote healthcare collaboration

Remote healthcare communication tools can be highly effective and useful for collaboration, clinical assessments, and surgical training, finds Ingo Aicher, Managing Director at Jones AV Limited.

Universal flu vaccine trial opens at NIH Clinical Center

A Phase 1 clinical trial of a universal flu vaccine has started inoculating healthy adult volunteers at the National Institutes of Health Clinical Center in Maryland.

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