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Drug Development

UCL leads €60m AI-driven drug discovery project launch

UCL joins global €60m AI-driven drug discovery initiative to generate open datasets and accelerate new medicines using AI models across disease areas.

AstraZeneca vaccines made for UK could be kept for EU use only

EU leaders today (25 March) decided not to create an export ban for AstraZeneca vaccines made for the UK - but the feud between AstraZeneca and the bloc remains close to the surface of future discussions.

Dexamethasone steroid saved one million people from COVID death

The Dexamethasone steroid has been used across the globe to help treat COVID-19 in the ICU - leading to atleast one million survivors of hospitalisation from the virus.

US trial finds AstraZeneca vaccine 100% effective against COVID death

In a study of over 32,000 people, a US trial found the AstraZeneca vaccine was 100% effective against deaths caused by COVID-19 - the vaccine did not show any connection to blood clots.

Polymers and polymer-based drug delivery in the treatment of dry eye disease

Professor Heather Sheardown, C20/20 Ophthalmic Materials Innovation Hub, Department of Chemical Engineering, McMaster University, explores how polymers can be used to treat dry eye disease.

European Medicines Agency say AstraZeneca does not cause blood clots

The safety committee of the European Medicines Agency said the investigation did not prove that AstraZeneca vaccinations cause blood clots - describing the possibility as an "extremely small likelihood".

European Commission says vaccine deliveries to UK could be stopped

President von der Leyen today (17 March) said that the Commission would limit vaccine deliveries to the UK if "the situation does not change" - suggesting that the drugmaker AstraZeneca is responsible for vaccination delays in the EU.

Birth control creates higher risk of blood clots than AstraZeneca vaccine

Currently, several EU countries are suspending use of the AstraZeneca vaccine due to reports of blood clot risks - in response, people are speaking out about the higher risk of blood clots posed by contraceptive pills used globally.

How global evidence can improve outcomes for spinal patients

Everard Munting, President of EUROSPINE, explains why sharing knowledge about spinal treatments on a global scale is the most effective way to develop best practice and enable early interventions.

European Medicines Agency says AstraZeneca vaccine still safe to use

Over the weekend, the Republic of Ireland suspended their use of AstraZeneca due to reports of blood clots in Norway - in response, the European Medicines Agency (EMA) says the AstraZeneca vaccine is still safe to use.

Diphtheria slowly becomes resistant to antimicrobial treatment

There is a well-established diphtheria vaccine taken by millions of people, but researchers are now observing the disease evolving a resistance to antimicrobial treatment.

Novavax 96.4% effective against the original COVID mutation

The US based vaccine appears to be 96.4% effective against the original COVID mutation, with 86% efficacy against the UK variant and only 55% against the South African variant.

How valuable are randomised controlled trials in reproductive medicine?

Professor Darren Griffin reflects on how patients in fertility clinics should interpret the scientific evidence base when even the experts can’t seem to agree.

Bharat Biotech COVID vaccine shows 81% efficacy at Phase Three

The Bharat Biotech COVID vaccine, COVAXIN, appears to be 81% efficient against the virus in Phase Three of clinical trials.

Scientists find that elevated neutrophils can predict severe COVID and death

Researchers at Yale believe that blood tests could predict severe or critical COVID cases, because blood holds a series of interesting biological signals about a person.

Israel will now vaccinate Palestinians who have permits to work 

Israel faced international criticism on their refusal to vaccine Palestinians - now, the country will begin rolling out Pfizer shots to some Palestinians who have work permits.

FDA approves the Johnson & Johnson vaccine for use

The US Food and Drug Administration (FDA) approved the Johnson & Johnson vaccine, with an efficacy of 86%, as the next to be rolled out across the US.

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