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Development of a new gene therapy drug as a treatment for hypophosphatasia
The current primary treatment for hypophosphatasia is enzyme replacement therapy; however the development of a new gene therapy drug, ARU-2801, may change the landscape forever.
The development of anti-infective drugs
University of Strathclyde’s Professor Colin J Suckling shares research being undertaken into anti-infective and immunomodulatory drug discovery programmes
Development of multiple drug resistance (MDR)
Terra G. Arnason and Troy A.A. Harkness from the Departments of Medicine, and Anatomy and Cell Biology at the University of Saskatchewan detail current strategies to prevent or reverse multiple drug resistant malignancy…
Multiple drug resistance (MDR) can be present from the outset (inherent) or develop (acquired) in response to...
The role of chemistry in drug discovery and development
Sriram Radhakrishnan, Healthcare Analyst at Frost & Sullivan details the vital role chemistry plays in drug discovery and development
Drug discovery and development is one of the most complex and expensive activities within the framework of the pharmaceutical industry. It encompasses a wide array of end-to-end activities with a plethora...
Are over-the-counter drugs an under-appreciated toxic danger?
OTC drugs are not harmless. Understanding the effects and dangers of OCT abuse and misuse is key to public safety, here UC Davis explains
Insights into autism development, treatment and management
Researchers from Japanese institutions have revealed insights into the molecular mechanisms underlying autism spectrum disorder (ASD).
Scientists discover cost-effective method to produce key drug molecules
Scientists at Scripps Research have revealed a new approach to synthesising crucial molecules used in drug development.
Development of novel therapies for pediatric cancer: Successes and challenges
Peter J. Houghton from Greehey Children’s Cancer Research Institute and Mary-Ann Bjornsti from the University of Alabama discuss some of the key challenges in the development of therapies for pediatric cancer care.
New machine-learning model identifies drug interactions for safer prescribing
Researchers have unveiled a new machine-learning approach to predict drug-accurate interactions.
Liverpool scientists awarded £1.4 Million to develop breakthrough malaria drug
Scientists from the University of Liverpool and Liverpool School of Tropical Medicine (LSTM) have taken a huge step forward in combating the global threat of malaria.
Can we do drug repositioning without disease gene expression?
Chuo University’s Professor Y-h. Taguchi examines the application of cutting-edge single-cell-based measurements in drug repositioning.
UK’s fascinating “AI for Development” vision at UN general assembly
The UK unveils its "AI for Development" vision at the UN General Assembly, emphasising how artificial intelligence (AI) can drive progress in the world's poorest nations.
£5 million fund to combat fatal drug deaths in the UK
In a concerted effort to combat the alarming issue of fatal drug deaths across the UK, the government has allocated £5 million to support 12 groundbreaking projects.
Researchers unravel HIV drug resistance mechanisms
The National Institutes of Health and Salk Institute researchers have made strides in understanding the molecular mechanisms behind HIV drug resistance mechanisms.
Investigating OTC drugs: Are over-the-counter drugs an under-appreciated toxic danger?
Contrary to popular belief, OTC drugs are not harmless. Understanding the effects and dangers of OCT abuse and misuse is key to public safety, here UC Davis provides everything you need to know.
Robotic pill safely delivers injectable Osteoporosis drug
A groundbreaking study demonstrates the efficacy of administering a previously injection-only medication for osteoporosis through an innovative robotic pill.
Understanding thermolabile protecting groups for nucleic acid-based drugs
Serge L. Beaucage investigates thermolabile protecting groups for the amine functions of purine and pyrimidine deoxyribonucleosides for the development and implementation of synthetic DNA sequences as nucleic acid-based drugs.
AI and anti-aging research: Unveiling the latest drug discovery
AI and Anti-aging research: According to a study, AI algorithms (AI) has led to the discovery of three drugs that have the potential to delay the effects of aging.
Progress in development of disease-modifying treatments in Parkinson’s Disease
Henri Huttunen, Chief Scientific Officer, Herantis Pharma Plc, charts progress in the development of disease-modifying treatments for Parkinson’s disease.
Brain gene which causes anxiety symptoms provides a novel drug target
Researchers have identified the gene in the brain which drives anxiety symptoms – which, if modified, could reduce anxiety levels.