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Drug development for Alzheimer’s disease
Alzheimer's disease (AD) is a major problem of health and a national priority in developed countries. Despite enormous efforts by governments, the scientific community and the pharmaceutical industry over the past 50 years, no therapeutic breakthroughs have yet been achieved, and the drugs available for the treatment of AD...
Development of a new gene therapy drug as a treatment for hypophosphatasia
The current primary treatment for hypophosphatasia is enzyme replacement therapy; however the development of a new gene therapy drug, ARU-2801, may change the landscape forever.
The development of anti-infective drugs
University of Strathclyde’s Professor Colin J Suckling shares research being undertaken into anti-infective and immunomodulatory drug discovery programmes
Development of multiple drug resistance (MDR)
Terra G. Arnason and Troy A.A. Harkness from the Departments of Medicine, and Anatomy and Cell Biology at the University of Saskatchewan detail current strategies to prevent or reverse multiple drug resistant malignancy…
Multiple drug resistance (MDR) can be present from the outset (inherent) or develop (acquired) in response to...
The role of chemistry in drug discovery and development
Sriram Radhakrishnan, Healthcare Analyst at Frost & Sullivan details the vital role chemistry plays in drug discovery and development
Drug discovery and development is one of the most complex and expensive activities within the framework of the pharmaceutical industry. It encompasses a wide array of end-to-end activities with a plethora...
£107m boost for Cardiff spin-out pioneering neuropsychiatric drugs
Cardiff University spin-out Draig Therapeutics has been awarded £107m ($140m) to advance the development of novel therapies for major neuropsychiatric disorders.
UK strives to become a global leader in AI-driven drug discovery
The UK Government is pushing itself to become a world leader in AI-powered drug discovery with new investments and global partnerships announced during London's Tech Week.
![Firing Neurons - 3d rendered image of Neuron cell network on black background. Conceptual medical illustration. Healthcare concept. SEM [TEM] view. Glowing neurons signals.](https://www.openaccessgovernment.org/wp-content/uploads/2025/05/iStock-2149152496-696x391.jpg "Experimental drug ‘Ulefnersen’ offers unprecedented hope for rare form of ALS")
Experimental drug ‘Ulefnersen’ offers unprecedented hope for rare form of ALS
An experimental drug known as ulefnersen has shown remarkable efficacy in treating a rare, aggressive form of ALS. Some patients experienced unprecedented functional recovery, offering new hope in a previously devastating diagnosis.
$2.7 Million NIH grant fuels development of first comprehensive syphilis test
Amidst a stark rise in US syphilis cases, researchers have secured a $2.7 million NIH grant to develop the first comprehensive, rapid test for active infection that aims to deliver accurate results within 10 minutes.
iDOMO: New AI tool predicts synergistic drug combinations
Researchers at Mount Sinai have developed iDOMO, a powerful AI tool that predicts synergistic drug combinations for complex diseases like cancer.
New genetic mutation linked to drug resistance in non-small cell lung cancer
A new case report details a novel genetic mutation linked to drug resistance in a non-small cell lung cancer patient. Researchers identified a RUFY1-RET fusion, highlighting the need for advanced genetic testing to guide treatment strategies and combat evolving resistance.
The latest developments in quantum computing: A transformative frontier
Quantum computing has been at the forefront of technological advancements, holding the potential to revolutionise fields ranging from cryptography to materials science.
New total-body PET scanner could transform drug discovery and early diagnosis
A new total-body PET scanner revealed at St Thomas' Hospital in London is up to 40 times more sensitive than previous scanners and is set to revolutionise how diseases are diagnosed and treated in the UK.
Advancing vaccine development for chlamydia
Genital Chlamydia trachomatis infection is a significant public health burden; Professor of Pediatrics and Microbiology and Immunology, Toni Darville, discusses the potential efficacy of CPAF-adjuvanted vaccines in mitigating the spread and impact of the infection.
Singapore and China research and development
Read an update about research and development in Asia, including in Singapore, plus health innovation in China by LSBF's Professor Preethi Kesavan.
Donanemab: NHS rejects second promising drug for Alzheimer’s
A second groundbreaking drug for Alzheimer's disease has been rejected for widespread use by the NHS in England; according to the drugs spending watchdog, the drug known as Donanemab does not offer sufficient value for money.
From drug disposal to water contamination: Unpacking pharmaceutical pollution
Lorna Rothery spoke to Health Care Without Harm (HCWH) Europe about the impact of pharmaceutical pollution and the barriers that need to be overcome to achieve a greener, more sustainable industry.
Osteoarthritis: disease development and treatments
Dr Deborah Lee of Dr Fox Online Pharmacy outlines the burden of osteoarthritis, how it can impact daily life, and emerging treatment options.
Are over-the-counter drugs an under-appreciated toxic danger?
OTC drugs are not harmless. Understanding the effects and dangers of OCT abuse and misuse is key to public safety, here UC Davis explains
Insights into autism development, treatment and management
Researchers from Japanese institutions have revealed insights into the molecular mechanisms underlying autism spectrum disorder (ASD).
