A first-in-patient trial using AAV-based OTOF gene therapy, led by Karolinska Institutet and Chinese hospitals, restored hearing (improving from 106 dB to 52 dB) in 10 individuals aged 1–24.
Pascale V Guillot from University College London, Elizabeth Garrett Anderson Institute for Women’s Health, explains stem cell and gene therapy to treat osteogenesis imperfecta, but is this hype or hope?
The study, published in PLoS Biology, looked at the neurotransmitter in the brain that calculates whether to pursue a task - in other words, motivation.
Here, we learn about Daisuke Kihara, Professor of Biological Sciences and Computer Science at Purdue University, who develops state-of-the-art computational methods for modelling 3D structures of protein complexes.
The study, published in The Lancet Digital Health, found that deep learning tech had an average accuracy of 88% when it came to diagnosing genetic syndromes.
Ute Deichmann of the Jacques Loeb Centre for the History and Philosophy of the Life Sciences at Ben-Gurion University, explores the role hierarchical causal models have on constancy and plasticity in biology.
A study, published in the journal DNA Repair, finds that hydroxychloroquine (HCQ) is potentially toxic to mammals - the drug that was previously elevated to the status of miracle COVID cure in some circles.
Dr Jen Vanderhoven, Director, National Horizons Centre, Teesside University, sheds some light on how the gene therapy field can progress in the face of funding challenges and skills shortages.
A team at Newcastle University have identified a gene, HLA-DRB1*04:01, which could be responsible for individuals who are asymptomatic - suggesting that the gene offers some protection against severe COVID.
Graham Brookes, Agricultural Economist with PG Economics, UK, charts how the development and deployment of COVID-19 vaccines, derived using techniques of genetic modification, highlight ideological inconsistency and hypocrisy.
Cecilia Van Cauwenberghe from Frost & Sullivan’s TechCasting Group, provides a portrait of a ground-breaking technology, next-generation sequencing, starting with a brief snapshot.
