DNA

Hidden DNA mutations in healthy people may reveal how cancer starts

Scientists using TwinsUK data and ultra‑precise DNA sequencing have uncovered rare mutations in healthy tissue that could help explain how cancer develops early in life.

‘Dark genome’ research suggests better treatment for mental disorders

Researching DNA outside of our genes, analysing the ‘dark genome’, scientists have found evolved proteins which can distinguish between schizophrenia and bipolar disorders, improving diagnosis and treatment.

The long-term effects of exposure to nanoparticles

In toxicology & health science focus, Ken Tachibana, Sanyo-Onoda City University in Japan, walks through the long-term effects of exposure to nanoparticles

What is a virus? An exploration for middle school students

Ann Matthysse, Department of Biology, University of North Carolina, explores what exactly a virus is, with a specific focus on RNA viruses and SARS-CoV-2.

Constancy & plasticity in biology – the central role of hierarchical causal models

Ute Deichmann of the Jacques Loeb Centre for the History and Philosophy of the Life Sciences at Ben-Gurion University, explores the role hierarchical causal models have on constancy and plasticity in biology.

Scientists use environmental DNA to calculate marine biodiversity

This study, conducted across the last 20 years on the kelp forests of Santa Barbara, examined marine biodiversity via environmental DNA.

Precision medicine: From bench to clinic

Here, we find out about Yourgene Health, a molecular diagnostics company with products and technologies that enable precision medicine in oncology from bench to clinic.

Resourceful solid-state nanopores: From blue energy production to big data processing

Jean-Pierre Leburton, and Olgica Milenkovic, Professors of Electrical and Computer Engineering at the University of Illinois at Urbana-Champaign, discuss how big data processing via bio-sensing, and blue energy production revolutionise solid-state nanopores.

How do environmental factors affect foetal development?

Associate Professor Ken Tachibana, discloses how prenatal ambient fine particle exposure disrupts DNA methylation and subsequent gene expression in the foetal development stage.

Ground-breaking technology: Next generation sequencing

Cecilia Van Cauwenberghe from Frost & Sullivan’s TechCasting Group, provides a portrait of a ground-breaking technology, next-generation sequencing, starting with a brief snapshot.

Next-generation sequencing to analyse biological tissues

Richie Kohman, Synthetic Biology Platform Lead at Wyss Institute at Harvard, explains the use of next-generation sequencing to analyse biological tissues in a spatially resolved context.

Application of ‘click chemistry’ ligation techniques to modified DNA and RNA

Professor Afaf El-Sagheer and Professor Tom Brown from the Department of Chemistry, Suez University and Oxford University describe their research, including the application of ‘click chemistry’ conjugation techniques to DNA.

Deep ocean drilling: Revealing earth history, geological processes and a deep biosphere

Virginia Edgcomb from the Woods Hole Oceanographic Institution discusses deep ocean drilling, a process that reveals earth history, geological processes and a deep biosphere.

Researchers discover marine fish DNA from 300 years ago

Ehime University researchers used samples from Japan to test if marine fish DNA existed in the same place for the last 300 years.

Single-cell genomics: Clinical strategies for COVID-19

Here, Cecilia Van Cauwenberghe from Frost & Sullivan’s TechVision Group argues that single-cell genomics empowers clinical strategies for COVID-19.

Machine learning will help to grow artificial organs

Researchers in Moscow and America have discovered how to use machine learning to grow artificial organs, especially to tackle blindness.

Gyrase and topoisomerase IV: Repurposing old targets for new antibacterials

Neil Osheroff from the Vanderbilt University School of Medicine is working to overcome drug resistance and revitalise the use of established targets for antibacterial agents, as we discover here.

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