drug development - search results

A view from one of the drug discovery teams at the University of Strathclyde, Glasgow, Scotland Earlier this year I completed a three-year term as a ‘Public Partner’ on the Scottish Medicines. Consortium (SMC), which is the body that advises the National Health Service in Scotland on the cost-effectiveness of medicines....

Open Access Government looks at how health research can play a pivotal role in preventing major diseases throughout the country  Over the decades we have changed the way we live, which can have a major impact on our health. For example, new technologies we use and the environment can all...

Although a small field in medicine, dermatological diseases are very frequent and span a wide range of illnesses such as allergies, inflammation (e.g. atopic dermatitis, psoriasis), autoimmune diseases or malignancies (e.g. melanoma). Thus, translational dermatological research is an important, innovative field for future basic and clinical research for many...

Hollie Chandler, Senior Policy Advisor at Cancer Research UK highlights the work being done to improve treatment for childhood cancers In the UK around 3,800 children, teenagers and young adults are diagnosed with cancer each year, that’s 73 every week. Thanks to new treatments, survival rates are improving. More than 80% of...

Nucleated blood platelets are produced by their bone marrow resident precursors, the megakaryocytes, in a unique process in mammalian physiology. Terminally differentiated, polyploid megakaryocytes are the largest cells in the bone marrow evolving from hematopoietic stem cells. Megakaryocytes are localised in close proximity to sinusoidal blood vessels and convert...

The European Confederation of Pharmaceutical Entrepreneurs (EUCOPE) is Europe’s principal trade body for small to medium-sized innovative companies working in the field of pharmaceuticals. Via its company members and national member associations such as the British Ethical Medicines Industry Group (EMIG), the German Pharmaceutical Industry Association (BPI), BioDeutschland, the...

Prioritising health research is an important mechanism for improving health, yet much of this research money is wasted, says the University of Nottingham

Denis Lacombe, John Bean and Mathilde Fenoulhet from the European Organisation for Research and Treatment of Cancer (EORTC) outline how clinical trials play an integral role in tackling cancer…  The European Organisation for Research and Treatment of Cancer (EORTC) is a European, academic, cancer clinical research organisation. A leader in...

A new treatment for pancreatic cancer could improve prognosis and increase survival rates… Research from the University of Ulster could change the outlook for people who develop pancreatic cancer. The university said the treatment discovery could see tumours reduce in size by five times. Pancreatic cancer is notoriously difficult to treat,...

Emerging research indicates that climate change impacts on mental health an increasing global concern Climate change is increasingly recognised as one of the greatest threats to human health of the 21st Century, with wide-ranging impacts on individuals, communities, and health systems globally. The latest synthesise evidence from the Intergovernmental Panel on Climate...

One of the most remarkable things about life on earth, in all its forms, is how cells often only tens of microns in diameter have evolved to carry out the variety of tasks that they do. In multicellular organisms, the situation is even more complicated, as different cell types...

OAG highlights the efforts made by the Welsh Government to improve cancer care and research throughout the country Due to an ageing population, the demand for cancer care is ever increasing. In Wales, cancer is one of the two biggest causes of premature death, which is why tackling the disease...

Professor Giles Vassal, President of the European Society for Paediatric Oncology outlines why it is crucial for Europe to come together and tackle and prevent cancer in children. Compared to the incidence in adults, cancer is rare in children and adolescents but concerns 35,000 young people each year in Europe. Despite...

Dr Masoud Dara, Senior Advisor at the World Health Organization explains the challenges of tackling TB to Editor Laura Evans, and why antibiotic resistance is such a problem… According to the World Health Organization, infectious diseases are caused by ‘pathogenic microorganisms, such as bacteria, viruses, parasites and fungi. Such diseases...

High content screening (HCS) is a remarkable technology that allows fully automated cellular imaging on a truly high-throughput scale. In the life and biomedical sciences it is now widely employed to solve questions in fundamental science, providing the research community with novel views on how cells function. In parallel, HCS...

Vittorio Cristini1,2, Eugene J. Koay3, and Zhihui Wang1,2 1Department of NanoMedicine and Biomedical Engineering, University of Texas Medical School at Houston, Houston, TX 77054, USA 2Brown Foundation Institute of Molecular Medicine, University of Texas Medical School at Houston, Houston, TX 77030, USA 3Department of Radiation Oncology, University of Texas MD Anderson Cancer...

Tom Stansfeld, Health Information Officer at Cancer Research UK gives an overview of breast cancer and how survival has improved… Breast cancer is the most common cancer in the UK with more than 50,000 new cases diagnosed each year. Over the last 40 years breast cancer incidence rates have gone...

Professor Alison Murray, Director of the Aberdeen Biomedical Imaging Centre, University of Aberdeen, explains how medical imaging has transformed healthcare over the years  Modern imaging is an essential part of healthcare and has come a long way since the discovery of X-rays in 1895 by Wilhelm Roentgen. Developments by researchers...

Dr Stefano Savonitto, Director of Cardiology at Manzoni Hospital sheds light on the risk of heart disease in women  When thinking about their health, women are especially concerned about cancer. However, the most frequent cause of death among women is heart disease and especially coronary artery disease. The number of...

The relationship between body composition and risk of disease has become more clearly understood in recent years, as the technology available to non-invasively quantify components of body mass has improved. Image-based approaches specifically and precisely quantify muscle and fat, while having the capacity to also reveal additional features such...