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Figure 1: Abnormal pain response in IBD and Endometriosis.

Therapeutic potential of the endocannabinoid system to treat chronic pain in inflammatory disease

Pharma researchers Julie Blaising and Philip Smith from F. Hoffmann-La Roche Ltd. discuss the endocannabinoid system as a pathway to treat inflammatory diseases such as Inflammatory Bowel Disease (IBD) and endometriosis.
Farmer pouring raw milk into container

Can cows create insulin? Transgenic cow opens doors for sustainable human insulin production

Researchers have successfully developed the world's first transgenic cow capable of producing human insulin in her milk.
Image: © peterschreiber.media | iStock

A guide for occipital neuralgia patients

Giorgio Pietramaggiori, MD, PhD and Saja Scherer, MD, from the Global Medical Institute, help us to understand occipital neuralgia in this detailed patient guide.
Patient talking with her doctor during an appointment in her office

Bariatric surgery opens doors for ESRD patients

Scientists have linked bariatric surgery with end-stage renal disease (ESRD) patients to see if it helps them become eligible for a kidney transplant.
Nurse preparing patient to do a blood analysis

Why giving blood is one of the best things you can ever do?

Ever thought about giving blood? Around 2.5 million litres of blood are transfused annually in the UK, but do we know about giving blood? Is it safe? What happens when you donate? Are there any risks? Here is all the information you need
Yellow tape measure in meters and inches in a spiral

The World Health Organization’s plan to tackle global obesity

A recent study published in The Lancet has revealed statistics regarding obesity, revealing that more than 1 billion individuals worldwide were struggling with obesity in 2022  Obesity rates among adults have more than doubled since 1990 and quadrupled among children aged 5 to 19 years. The struggles of undernutrition and obesity  The...

UK gender gap in health: How can remote monitoring create fair female healthcare?

Natalie Duffield explains how Inhealthcare – a UK leader in digital health and remote monitoring – is helping NHS organisations to develop and deliver technologies that can help close the gender gap in health outcomes and provide fair access to women’s clinical services.
x chromosome,Human genome concept

Insights on metabolic health and reproductive wellness with Dr. Carol Elias

In this exclusive interview, Dr. Carol Elias simplifies the complex link between metabolism and reproduction, sharing insights into the science behind our physiological balance.
Medical Marijuana Buds

Cannabis use linked to increased risk of heart attack and stroke

Analysis of over 430,000 adults in the United States has unveiled concerning connections between cannabis consumption and heightened risks of heart attack and stroke.
Prisoners communicating during walk, Understanding and supporting neurological conditions among the incarcerated

Understanding and supporting neurological conditions among the incarcerated

Samuel Han and Audrey Nath discuss neurological conditions among the incarcerated, who they argue are a medically underserved population.
Ensuring her vitals are nominal before the procedure

New scientific statement raises awareness of heart disease risks for women

Recent evidence reveals the risks and challenges women face regarding heart disease, emphasising the urgent need to prioritise heart health among women.
FIGURE 1 The gap in research paradigms: turning evidence into relatable narratives.

Beyond the numbers: COVID-19 data miscommunication

Prof Giampiero Favato and Cristina Oliva, MD, explain how storytelling shapes health behaviours beyond the numbers. Here, we learn lessons from COVID-19 data miscommunication.
Close up of a stethoscope and digital tablet with virtual electronic medical record of patient on interface.Digital healthcare and network on modern virtual screen, DNA medical technology and futuristic concept.

Leveraging innovations in health tech to mitigate health care disparities

From desktops to laptops, smartphones to smartwatches, technology has come to play an increasingly central role in our lives, but what about health tech? And as the influence of technology has spread across industries, crucial sectors like education and healthcare have seen noticeable transformations.
Taking an insulin shot at home

Oral insulin delivery: A smarter solution for insulin management

Scientists have discovered a way to supply insulin to the body, which could benefit the lives of 425 people worldwide battling with diabetes.
Glucowear Charger Oct 2023.bip.308

Should the wider population be paying attention to their blood sugar levels?

Diabetes represents a huge burden on health systems and sufferers, but accurately monitoring blood sugar levels could help people to take control of their health before more serious issues come to light.

The link between placental growth factor and pregnancy complications

Ernesto Figueiro-Filho and Karolina Grzyb from the University of Saskatchewan discuss the role of placental growth factor (PlGF) in screening for preeclampsia and adverse obstetric outcomes in diabetic populations

Digital Life Norway (DLN) Initiative to foster and boost transdisciplinary biotechnology research and innovation

Meeting the rapid developments in biotechnology by fostering transdisciplinarity, including digitalisation and big data, to create convergence for innovation in a virtual centre.
Abstract Lactobacillus Bulgaricus Bacteria - 3d rendered microbiology image. Medical research, health-care concept. SEM (TEM)scanning view

Sepsis Canada: Building a national research network for sepsis awareness

Sepsis is a life-threatening condition estimated to affect 49 million people annually worldwide; yet it is not widely understood. In this article, we hear how Sepsis Canada is working to promote sepsis awareness through supporting research, public education, and cross-disciplinary training.
Mature man helps younger man verbalize problems in therapy

Breaking the stigma: Men’s mental health matters

Dr Deborah Lee from Dr Fox Online Pharmacy discusses men’s mental health, including common barriers to seeking help and the measures needed to improve overall awareness and support.
Figure 1. Two routes of brain infection by which SARS-CoV-2 may enter the hypothalamus and infect GnRH neurons. The virus attaches to and enters cells harbouring surface receptors such as ACE2 (black spanner-like symbol) or NRP1 (red cylinder). GnRH neurons exhibit both, which might increase their vulnerability. A. The haematological route, whereby the respiratory virus (white spheres) makes its way through the lungs into the bloodstream (dark red), and thence into the median eminence (ME), a part of the hypothalamus that harbours ”fenestrated” or leaky blood vessels. The virus may affect a number of different cell types locally, including GnRH neurons (green), whose secretory terminals approach the fenestrated vessels, and tanycytes (grey), whose processes control this secretion and also transport other bloodborne hormones and other substances into the brain. Once inside the brain ventricles (V), fluid-filled canals within the brain, the virus can also travel to other areas. B. The olfactory route, whereby the virus enters the olfactory bulb (OB) of the brain directly from the nose across the bony cribriform plate by means of nerve bundles or infected olfactory neurons and other cell types. GnRH neurons, which are born in the nasal epithelium during the embryonic period and migrate into the brain along these nerve bundles to their final positions, still maintain a connection with their birthplace, and could be thus be infected directly or indirectly through olfactory neurons or other cells. GnRH neurons also project to parts of the brain involved in higher functions such as cognition, potentially contributing to long-COVID symptoms such as “brain fog”.

Brain infection by SARS-CoV-2: Lifelong consequences

The WATCH team, founded to elucidate the role played by specialized brain cells called tanycytes in various physiological processes, has been investigating how and where the SARS-CoV-2 virus infects the brain, and some long-term consequences of this neuro-invasion.

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