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By providing the infrastructure to support drug discovery, the IMI is accelerating access to innovative medicines, as the EFPIA highlights here Innovation is the lifeblood of the pharmaceutical industry, providing us with the potential to cross new therapeutic frontiers to bring novel medicines to market that benefit patients and deliver...

Stroke is a major cause of morbidity and mortality worldwide, but research into spontaneous brain plasticity could offer hope for recovery Among the main causes of brain injury, ischemic or haemorrhagic stroke burdens the life of hundreds of thousands of people each year. Approximately half of the survivors are susceptible...

Dr Sumith A Kularatne, vice-president of R&D at On Target Laboratories, explores the pros and cons of various existing treatments for prostate cancer Prostate cancer (PCa) is the second leading cause of cancer-related deaths in men, with about 1.1 million new cases and approximately 307,000 fatalities per year globally. This...

Improving cancer survival relies on earlier diagnosis, but diagnostic services are under growing pressure, as Cancer Research UK Policy Manager Sara Bainbridge explains There are more than 200 different types of cancer, so when someone sees their doctor with possible symptoms, getting the right diagnosis can be complicated. Diagnosing cancer...

Professor Pierre Ronco describes advances in our understanding of membranous nephropathy and the promise of precision medicine to treat the disease A rare disease which affects the kidney, membranous nephropathy is the second-most common cause of nephrotic syndrome, which is characterised by massive protein loss in the urine. The consequence...

Jo Vandesompele, Chief Scientific Officer at Biogazelle, outlines how non-coding RNA research for cancer can help develop a more targeted treatment approach  DNA is the hereditary code that is passed on from parents to their children. Every cell inside our body has the same code that contains the blueprint of...

Zhihui Wang1,2 and Vittorio Cristini1,2   outline how they have developed a model to help predict cancer treatment outcomes… The physical properties of a tumour’s microenvironment influence a drug’s ability to penetrate and kill tumour cells. Some of these properties can be potential obstructions to drug diffusion, increasing the tumour’s resistance...

Dr. Ana Terrés, Director of Research Support at Dublin City University (DCU), looks at how DCU innovates for societal impact and contributes to Ireland’s economic recovery… Dublin City University (DCU) is a young and dynamic university which aims to have an impact on Irish society, not only by placing...

Ai-Ling Lin, Ph.D, Assistant Professor, Sanders-Brown Center on Aging, University of Kentucky discusses Alzheimer's disease and the link to diabetes and nutrition... Alzheimer’s disease (AD) is the most common form of dementia in those over the age of 65, and currently ranked as the sixth leading cause of death in the United...

Cancer is a complex and heterogeneous disease. Despite all efforts to fight cancer, it continues to impact every segment of society. For example, many patients fail conventional cancer therapies, including chemotherapy, radiation, and surgery; and it is still difficult for physicians to predict a treatment outcome with certainty.

Dr Justin Warner, Clinical Lead for the National Paediatric Diabetes Audit at the Royal College of Paediatrics and Child Health details how continued improvements in diabetes care for children is needed in England and Wales… According to latest statistics, the outcomes for children and young people with type 1 diabetes...

A new class of nanotherapy blockades the genetic drive for multiple myeloma progression. Gregory M. Lanza and Michael H Tomasson, of Department of Medicine, Washington University School of Medicine explain... Multiple myeloma is malignancy of plasma cells that reside in the bone marrow and normally function as part of our immune defence...

Nucleated blood platelets are produced by their bone marrow resident precursors, the megakaryocytes, in a unique process in mammalian physiology. Terminally differentiated, polyploid megakaryocytes are the largest cells in the bone marrow evolving from hematopoietic stem cells. Megakaryocytes are localised in close proximity to sinusoidal blood vessels and convert...

The Clinic of Nuclear Medicine at the University Hospital is located both in Düsseldorf and at the Research Center Jülich, and runs a nuclear medical out-patient department covering the whole spectrum of radioisotope scanning from thyroid and skeleton scintigraphy to examinations of amino acid metabolism for tumor diagnosis. As...

AG highlights the work of the National Cancer Institute (NCI), to reduce and treat cancer. The National Cancer Institute (NCI) is the U.S. Federal government’s primary agency for cancer research and training. As part of the National Institutes of Health (NIH) they coordinate with the National Cancer Programme, which conducts...

Vittorio Cristini1,2, Eugene J. Koay3, and Zhihui Wang1,2 1Department of NanoMedicine and Biomedical Engineering, University of Texas Medical School at Houston, Houston, TX 77054, USA 2Brown Foundation Institute of Molecular Medicine, University of Texas Medical School at Houston, Houston, TX 77030, USA 3Department of Radiation Oncology, University of Texas MD Anderson Cancer...

The government is outlining radical changes aimed at boosting the number of apprenticeships and improving the quality of training courses. The apprenticeship levy received a mixed reception after it was announced, but the government said it will level the playing field, enabling all companies to take part in delivering the...

Pressure at Worcestershire Royal Hospital has led to a doctor who is usually drafted in to tackle major disasters being brought in... Health bosses have admitted they have been forced to bring in a doctor who is usually on call for major disasters in a bid to tackle problems facing...

 A new report has warned that a significant number of children with type 1 diabetes are at risk of long term health complications... The future health of children with type 1 diabetes is of great concern, according to a new report. A “worryingly high” number of young people are showing...

Cancer is an unreliable disease. Just as you think you are familiar with it and can begin treating and hopefully curing it, it is no longer as you thought it was. It has coloured its hair, carries other garments, or has changed its lifestyle making it unrecognisable and impossible...